When looking at the title of this article, it would be easy to assume that it refers to the rise and fall of the Neo-Babylonian Empire, which existed from 626 BC to 539 BC. However, this article is not referring to that past empire but to the future city of Babylon.

In Isaiah 13, we read of the fulfilled prophecy concerning the end of Neo-Babylon’s prominence when Cyrus the Great and the Medo-Persian Empire defeated the Babylonians (see verses 17–18). However, the chapter also points to the destruction of the city itself in verses 19–20, which state: “And Babylon, the glory of kingdoms, the beauty of the Chaldeans’ pride, will be as when God overthrew Sodom and Gomorrah. It will never be inhabited, nor will it be settled from generation to generation; nor will the Arabian pitch tents there, nor will the shepherds make their sheepfolds there.”

What is often overlooked in this passage is that it states that the city of Babylon will be completely destroyed, like Sodom and Gomorrah, and that, like those cities, it will remain desolate after its destruction. The problem, however, is that history does not appear to support this interpretation!

When Cyrus defeated Babylon, he did so without a major battle, as suggested by the Nabonidus Chronicle and the Cyrus Cylinder. The Greek historian Herodotus also describes how Cyrus diverted the Euphrates River, allowing his forces to enter the city through the riverbed and gain access beneath its defenses. Thus, Babylon was captured without a major battle. Finally, Daniel 5 narrates the final moments of the Neo-Babylonian Empire and the life of King Belshazzar, yet it does not describe a battle or the destruction of the city itself.

There is also considerable evidence that Babylon was not left desolate after Cyrus the Great conquered it. In fact, history tells us that Alexander the Great made Babylon his headquarters in 323 BC, shortly before his death. Centuries later, Babylon remained an important center of Jewish scholarship, and the Babylonian Talmud was compiled in stages during the first several centuries AD, with its major collections reaching their final forms around the fifth and sixth centuries. Therefore, ancient Babylon was neither destroyed like Sodom and Gomorrah nor left desolate immediately following its fall.

Although Babylon eventually became desolate, I do not believe Isaiah’s prophecy allows us to conclude that its present condition represents the prophecy’s ultimate fulfillment. I believe this ancient city will rise to prominence and glory before being destroyed, as Isaiah’s prophecy demands.

We see a similar picture in Revelation 18, which, in my interpretation, points to the future grandeur of this ancient city. For example, in verse 11, Babylon is described as a place where merchants mourn the loss of their trade, while verses 16–17 portray its immense wealth, including gold, precious stones, and pearls.

This chapter also describes Babylon’s destruction. Verses 10 and 17 state that its judgment comes in “one hour,” emphasizing the suddenness of its downfall. In verses 9 and 18, observers see the smoke of its burning. Additionally, verse 8 declares that it will be consumed by fire. These details, in my view, parallel the prophecy in Isaiah 13:19–20.

Finally, it is not beyond reason to consider the possibility that Babylon could once again become a great city. It lies along the Euphrates River, with the Tigris River flowing to the east. Both rivers form part of the broader Mesopotamian river system, which connects to the Persian Gulf. The region’s historical importance as a center of trade and commerce makes it possible to envision Babylon becoming prosperous again. Therefore, the description of Babylon as a wealthy commercial center in Revelation 18 is not necessarily far-fetched, giving us further reason to reexamine Isaiah’s prophecy.